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Research Assistant

QIMR Berghofer Medical Research Institute

Brisbane, Queensland, Australia

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Job Posted: 12/07/2018

Job Category:

Science & Technology / Research & Development

Job description:

About QIMR Berghofer:

QIMR Berghofer is a world-leading translational medical research institute focused on improving health by developing new diagnostics, better treatments and prevention strategies, specifically in the areas of cancer, infectious diseases, mental health and chronic disorders. Based in Herston, Brisbane and working in close collaboration with clinicians and other research institutes, QIMR Berghofer is home to more than 600 scientists, students and support staff.


About the Tumour Immunology Laboratory:

The major goal of the Tumour Immunology Laboratory is to obtain a deeper understanding of the mechanisms by which an immune response to tumours may be generated, augmented and applied to the inhibition of tumour growth.


Role Purpose / Responsibilities :

This position offers the opportunity to develop immune-based therapies for Epstein-Barr virus and cytomegalovirus-associated diseases.

You will be responsible for:

  • Developing and validating single and multiplex immunohistochemistry (IHC) assays.
  • Assisting in Imaging of tissue sections using automated microscopy, and running image analysis pipelines using manual and automated image analysis softwares.
  • Conducting experiments using standard techniques of molecular biology/biochemistry and cell culture (DNA/RNA extraction, PCR, ELISA, western blotting)
  • In addition, you may be also involved in processing blood and tissue samples from patients participating in the clinical trials.


About you:

To be successful, you will have an Honours degree in immunology, biochemistry, molecular biology or a related biological science.

The following technical knowledge and experience is essential;

  • Histopathological techniques such as tissue sample preparation, IHC assay development, collecting images with IHC and IF (minimum 4 fluoroscent dyes) staining, digital pathology; sterile tissue culture techniques, including maintenance of human cell lines and primary cultures.
  • Ability to troubleshoot and find solutions for histotechnological and immunfluoroscence challenges.
  • Familiarity with whole slide scanners (Aperio, Zeiss, and/or Perkin Elmer) and existing image analysis software packages such as imageJ, Definiens) is a plus.
  • Meticulous attention to detail.
  • Working both autonomously and co-operatively within team is critical.